In a large saucepan, bring the wine, sugar, honey, and cinnamon stick to a boil. Split the vanilla bean lengthwise and scrape out the seeds. Add the seeds and pod to the saucepan.
Add the nectarines and enough water to cover them. Simmer gently until tender, 12 to 15 minutes. Transfer the nectarines to a large bowl.
Simmer the liquid until reduced to 1 cup, 12 to 15 minutes. Discard the vanilla pod. Pour the liquid over the nectarines. Refrigerate until chilled, 50 to 60 minutes.