A. Grab the liquid dish detergent. Standard liquid dish detergent can help safely remove lipstick and lip-liner stains from most cotton or polyester handbag linings. (For all other materials, it’s best to take the bag to a dry cleaner.) To apply, dilute a capful of dish detergent with an equal amount of warm water. Pull the lining as far out of the bag as you can. Then, using a cotton swab, apply the mixture to the stain in a circular motion, says clothing-care expert Steve Boorstein. Switch swabs often so you don’t rub the pigment back into the fabric. Allow the bag to air-dry. Repeat until the stain is removed.
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