Best for: Trips lasting a full day or more.
How it works: The patch, sold under the brand name Transderm Scōp, contains the drug scopolamine. Worn behind the ear, it works similarly to antihistamines—by interfering with the communication between nerves and the part of the brain that controls vomiting. But it’s longer-lasting than antihistamines, releasing a steady dose of medication over three days, says Brent Rieger, an internist at Loyola University Medical Center, in Chicago. Apply the patch at least four hours before travel.
Good to know: Wash your hands thoroughly after applying, as the medication can temporarily blur your vision if it gets in your eyes.