The skin around the lips, called the perioral region, is the first to show signs of aging. Movement of muscles in the face when you talk, smile, and laugh weaken collagen, resulting in creases. To minimize this process, use a pea-size drop of retinol cream nightly on the area (don’t quit smiling and laughing). If your skin is sensitive, apply every other night. Try Dermelect Cosmeceuticals Smooth Upper Lip & Perioral Anti-Aging Treatment.
To buy: $38, dermelect.com.